Though the usual instinct when choosing a hotel in a European capital is to opt for a central location, sometimes a city is best discovered from a real-people neighborhood instead. The handsome new 78-room URSO Hotel & Spa is located in the up-and-coming Salesas district, which has much in common with New York City’s Greenwich Village or London’s Notting Hill. An arty and atmospheric area with lots of one-of-a-kind boutiques and excellent restaurants, it is nonetheless just 15 minutes from the Prado museum, ground zero for most visitors to Madrid.