Above: Golden Eagle Luxury Trains' Trans-Siberian Express rides along Lake Baikal in Russia

TheVenice Simplon-Orient-Expresslooms large in legend, thanks to Agatha Christie, who chose it as the setting for her 1934 detective novelMurder on the Orient Express. Now part of the Belmond collection of properties and luxury trains, theVenice Simplon-Orient-Expressoffers its classic London-Paris-Venice route (as well as Venice-Paris-London) several times a year. But the route features only one overnight on board. Those who hunger for something longer should consider one of the signature journeys, which follow a route similar to the one that the train debuted with in 1883. Both theParis to Istanbuland theIstanbul to Veniceitineraries are offered once a year and last five nights, with three of those spent aboard the train. Both also include a tour of Budapest, a cruise on the Danube river and a visit to Peles castle in Romania.

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Above: Golden Eagle Luxury Trains' Trans-Siberian Express rides along Lake Baikal in Russia